BDBM12655 (1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-trifluorophenyl)cyclohex-3-en-1-aminium; 2,2,2-trifluoroacetate::ABT-341 analogue 22

SMILES NC(=O)c1cccc(NC(=O)C2=CC[C@@H]([C@@H]([NH3+])C2)c2cc(F)c(F)cc2F)c1

InChI Key InChIKey=XXQAXMIQRFUFDQ-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12655   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12655((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...)
Affinity DataKi:  4.70nM ΔG°:  -11.2kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12655((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...)
Affinity DataKi:  8.80E+3nM ΔG°:  -6.82kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12655((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...)
Affinity DataKi:  1.40E+4nM ΔG°:  -6.55kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed