BDBM12765 1-(3-carbamimidoylphenyl)-N-[2-fluoro-4-(1H-indol-1-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::pyrazole analog 3n

SMILES NC(=N)c1cccc(c1)-n1nc(cc1C(=O)Nc1ccc(cc1F)-n1ccc2ccccc12)C(F)(F)F

InChI Key InChIKey=IOUJEXDJFKAVEA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12765   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM12765(1-(3-carbamimidoylphenyl)-N-[2-fluoro-4-(1H-indol-...)
Affinity DataKi:  5.40nM ΔG°:  -11.2kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM12765(1-(3-carbamimidoylphenyl)-N-[2-fluoro-4-(1H-indol-...)
Affinity DataKi:  1.70E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed