BDBM12921 4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole::CHEMBL425274::Glycoconjugate Benzene Sulfonamide 3aa::{1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-1H-1,2,3-triazol-4-yl}methyl 4-sulfamoylbenzoate

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCc1cn(nn1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=KMZODUVSKUKAQG-UXXRCYHCSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 12921   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  7nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human recombinant CA12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  58nMAssay Description:Inhibition of human recombinant CA14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  183nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  183nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  4.40E+3nM ΔG°:  -7.30kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

LigandPNGBDBM12921(4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed