BDBM129358 US8802686, 16

SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCCC3)n2)C(F)(F)F)cc1

InChI Key InChIKey=LMOGABSWSZHKQR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 129358   

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM129358(US8802686, 16)
Affinity DataIC50: 480nMpH: 8.0 T: 2°CAssay Description:CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM129358(US8802686, 16)
Affinity DataIC50: 890nMpH: 5.5 T: 2°CAssay Description:VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM129358(US8802686, 16)
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent