BDBM13226 2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2-methylphenyl)-1,3-thiazole-5-carboxamide::BMS-354825 tert-Butoxycarbamate Analog 5g::CHEMBL128568::tert-butyl N-{4-methyl-5-[(2-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}carbamate

SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1ccccc1C

InChI Key InChIKey=XVOOJFPXKZNAOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13226   

TargetProto-oncogene tyrosine-protein kinase LCK(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13226(tert-butyl N-{4-methyl-5-[(2-methylphenyl)carbamoy...)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of mouse p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase LCK(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13226(tert-butyl N-{4-methyl-5-[(2-methylphenyl)carbamoy...)
Affinity DataIC50: 4.57E+4nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed