BDBM13232 2-(2-furoylamino)-N-mesityl-4-methyl-1,3-thiazole-5-carboxamide::2-N-(furan-2-)-4-methyl-5-N-(2,4,6-trimethylphenyl)-1,3-thiazole-2,5-diamido::BMS-354825 2-Amino-4-methyl-thiazole Analog 7f::CHEMBL131661

SMILES Cc1nc(NC(=O)c2ccco2)sc1C(=O)Nc1c(C)cc(C)cc1C

InChI Key InChIKey=KMFDWSKWECMQEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13232   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13232(CHEMBL131661 | 2-N-(furan-2-)-4-methyl-5-N-(2,4,6-...)
Affinity DataIC50: 360nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13232(CHEMBL131661 | 2-N-(furan-2-)-4-methyl-5-N-(2,4,6-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed