BDBM132347 US8841312, 93

SMILES O=S1(=O)CCC(C1)Nc1ccc(Nc2ncc3c(n2)n(C2CCCC2)c2cnccc32)nn1

InChI Key InChIKey=XWJNDQQXLCXSQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132347   

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM132347(US8841312, 93)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandPNGBDBM132347(US8841312, 93)
Affinity DataIC50: 15.9nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent