BDBM132354 US8841312, 100

SMILES C(Nc1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nn1)C1COCCN1

InChI Key InChIKey=AYVQZFAABNRPNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132354   

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM132354(US8841312, 100)
Affinity DataIC50: 6.20nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent