BDBM13269 BMS-354825 2-Heteroarylamino-thiazole Analog 12n::CHEMBL186564::N-(2-chloro-6-methylphenyl)-2-[(4,6-dimethylpyrimidin-2-yl)amino]-1,3-thiazole-5-carboxamide

SMILES Cc1cc(C)nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)n1

InChI Key InChIKey=LMFMPTPURHABEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13269   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13269(CHEMBL186564 | N-(2-chloro-6-methylphenyl)-2-[(4,6...)
Affinity DataIC50: 50nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed