BDBM134311 US8846658, 22

SMILES CC1(COCC(N)=N1)c1cccc(NC(=O)c2ccc(cn2)C(F)(F)F)c1

InChI Key InChIKey=VZIVJCUBWLYNSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134311   

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134311(US8846658, 22)
Affinity DataIC50: 420nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent