BDBM134425 US8846658, 142

SMILES Cc1cc(n[nH]1)C(=O)Nc1ccc(F)c(c1)[C@@]1(COCC(N)=N1)C(F)F

InChI Key InChIKey=KJIDRFGYFHIELN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134425   

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134425(US8846658, 142)
Affinity DataIC50: 820nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent