BDBM136695 US8865686, Table 1, Compound 7

SMILES CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(C(=O)NCCO)=C1O)C(=O)c1c(O)cccc1C3(C)O

InChI Key InChIKey=LXWCAVKCXCTKMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136695   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandPNGBDBM136695(US8865686, Table 1, Compound 7)
Affinity DataIC50: 1.22E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent