BDBM136954 US20250017938, Compound 001-5::US8871790, 5

SMILES CC(C)S(=O)(=O)N1CCc2nc([nH]c2C1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C

InChI Key InChIKey=IYXPXGIUOLJNCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136954   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM136954(US8871790, 5 | US20250017938, Compound 001-5)
Affinity DataIC50: 55nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM136954(US8871790, 5 | US20250017938, Compound 001-5)
Affinity DataIC50: 55nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent