BDBM137205 US8871790, 275

SMILES CCc1nnc([nH]1)-c1cc(ccc1C)C(=O)N1CCC(CC1)c1ccc(cc1)C#N

InChI Key InChIKey=IPLXJGHXXXZKRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 137205   

TargetFatty acid synthase(Human)
Sagimet Biosciences

US Patent
LigandPNGBDBM137205(US8871790, 275 | US20250017938, Compound 001-275)
Affinity DataIC50: 2.25E+3nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetFatty acid synthase(Human)
Sagimet Biosciences

US Patent
LigandPNGBDBM137205(US8871790, 275 | US20250017938, Compound 001-275)
Affinity DataIC50: 2.25E+3nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent