BDBM138357 US10278929, Compound 6::US11337935, Compound 6::US8877795, 6

SMILES COc1ccc(\C=N\n2c(S)nnc2C(F)(F)F)cc1O

InChI Key InChIKey=ZIYNKKNAQUMLPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 138357   

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US8877795, 6 | US10278929, Compound 6 | US11337935...)
Affinity DataIC50: 277nMAssay Description:The FP assay was then adapted for HTS and used to screen a 120,000 member small molecule library for compounds that displaced the FP probe from the T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US8877795, 6 | US10278929, Compound 6 | US11337935...)
Affinity DataIC50: 277nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US8877795, 6 | US10278929, Compound 6 | US11337935...)
Affinity DataIC50: 277nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent