BDBM139103 US8883771, 49

SMILES CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)NCCCCCCNC(=O)N2CC[C@H]3CC[C@@H](C(=O)N[C@H]4C[C@H](c5ccccc5)C4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CCC(C(=O)N[C@H]3C[C@H](c4ccccc4)C3)N2C1=O

InChI Key InChIKey=WQMKNMZJGAAGQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139103   

TargetE3 ubiquitin-protein ligase XIAP(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 139103BDBM139103(US8883771, 49)
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 139103BDBM139103(US8883771, 49)
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 139103BDBM139103(US8883771, 49)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent