BDBM13942 2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE::APC-8328::{amino[2-(2-hydroxyphenyl)-1H-indol-5-yl]methylidene}azanium

SMILES NC(=[NH2+])c1ccc2[nH]c(cc2c1)-c1ccccc1O

InChI Key InChIKey=JPGNPKIYCTXJPG-UHFFFAOYSA-O

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13942   

TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13942(2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE | A...)
Affinity DataKi:  740nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13942(2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE | A...)
Affinity DataKi:  880nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13942(2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE | A...)
Affinity DataKi:  1.70E+3nM ΔG°:  -7.79kcal/molepH: 7.5 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13942(2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE | A...)
Affinity DataKi:  3.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed