BDBM139649 US8894989, 27

SMILES O=C(c1ccccc1C(F)(F)F)N1CCCN(CC2=Nc3cccc4c(=O)[nH]nc(c34)N2)CC1

InChI Key InChIKey=HMEPCVZSVIWCBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139649   

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandChemical structure of BindingDB Monomer ID 139649BDBM139649(US8894989, 27)
Affinity DataIC50: 43nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent