BDBM139808 US8895581, II-29

SMILES CC(C)n1c(C)nc2cnc3ccc(cc3c12)C#CCNC(=O)c1cccn(CC2CCCOC2)c1=O

InChI Key InChIKey=AWDUJZUZDGELON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139808   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM139808(US8895581, II-29)
Affinity DataIC50: 202nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent