BDBM140289 US8912173, 15

SMILES COc1c(F)cc(cc1F)-c1cc(OC[C@H]2CNC(=O)O2)c2cccnc2c1

InChI Key InChIKey=PCGVPRVQUYAZGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140289   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140289(US8912173, 15)
Affinity DataIC50: 16.2nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent