BDBM14151 APC-9850::{amino[6-chloro-2-(3,5-dichloro-2-hydroxyphenyl)-1H-indol-5-yl]methylidene}azanium

SMILES NC(=[NH2+])c1cc2cc([nH]c2cc1Cl)-c1cc(Cl)cc(Cl)c1O

InChI Key InChIKey=BWMVXULSVHMQIK-UHFFFAOYSA-O

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 14151   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  300nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  310nM ΔG°:  -8.78kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  1.90E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  4.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  4.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceutical

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  9.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  9.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  1.70E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  1.70E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  3.20E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed