BDBM142813 US8940736, 269

SMILES FC(F)c1cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c(Cl)c(c1)N1CCN(CC1)C1(CS(=O)(=O)c2ccccc2)COC1

InChI Key InChIKey=AQXKWRSZCYMQDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142813   

TargetCasein kinase II subunit alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142813(US8940736, 269)
Affinity DataIC50: 13.9nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetCasein kinase II subunit alpha'(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142813(US8940736, 269)
Affinity DataIC50: 3.16nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent