BDBM14332 2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cyclopentyloxy)benzen-1-olate::CRA-10433

SMILES NC(=[NH2+])c1ccc2[nH]c(cc2c1)-c1cccc(OC2CCCC2)c1[O-]

InChI Key InChIKey=CFSQPEBVGUSQII-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14332   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14332(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cy...)
Affinity DataKi:  68nM ΔG°:  -9.67kcal/molepH: 8.06 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14332(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cy...)
Affinity DataKi:  190nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14332(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cy...)
Affinity DataKi:  700nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14332(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cy...)
Affinity DataKi:  1.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14332(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cy...)
Affinity DataKi:  7.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed