BDBM143406 US8969341, 55

SMILES CC(C)c1c2C(N(C(=O)c2nn1Cc1ccccc1)c1cccc(Cl)c1F)c1ccc(Cl)cc1C

InChI Key InChIKey=WPSSCIDRUBTKAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143406   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 143406BDBM143406(US8969341, 55)
Affinity DataIC50: 24.2nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
US Patent