BDBM144465 US8969568, 16

SMILES COc1ccc(cc1Cl)-c1cc2ncccc2c(OC[C@H]2CNC(=O)C2)n1

InChI Key InChIKey=NIORITCVKCMJBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144465   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144465(US8969568, 16)
Affinity DataIC50: 7.20nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
Go to US Patent