BDBM144834 US8952157, 16::US9303025, 16

SMILES CN(C)CCCNc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cccc2n(C)ccc12)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1

InChI Key InChIKey=IRXDZEBBPLUJNH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144834   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM144834(US8952157, 16 | US9303025, 16)
Affinity DataKi:  3.04nM ΔG°:  -11.6kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM144834(US8952157, 16 | US9303025, 16)
Affinity DataKi:  3.04nM ΔG°:  -11.6kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent