BDBM145207 US8952157, 398::US9303025, 398

SMILES CN(C)CCOc1cccc(c1CN1CCN(CC1)c1ccc(C(=O)NS(=O)(=O)c2ccc(NCC3CCOCC3)c(c2)[N+]([O-])=O)c(Oc2cnc(N)c(Cl)c2)c1)-c1ccc(Cl)cc1

InChI Key InChIKey=BJPBRFVPMQIASB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145207   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM145207(US8952157, 398 | US9303025, 398)
Affinity DataKi:  0.175nM ΔG°:  -13.3kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM145207(US8952157, 398 | US9303025, 398)
Affinity DataKi:  0.175nM ΔG°:  -13.3kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent