BDBM145980 US8957068, 15

SMILES C[C@H](Nc1nccc(n1)N1[C@@H](C)[C@H](OC1=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=SQROIPJYQITCDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145980   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Novartis

US Patent
LigandPNGBDBM145980(US8957068, 15)
Affinity DataIC50: 5.38E+3nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2015
Entry Details
US Patent