BDBM146003 US8957068, 38

SMILES C[C@@H](Nc1nccc(n1)N1[C@H]([C@H](OC1=O)c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=AJQFGMMZAYJUHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 146003   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Novartis

US Patent
LigandPNGBDBM146003(US8957068, 38)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2015
Entry Details
US Patent