BDBM147504 US8962608, 9

SMILES NCC1CCC([C@@H](C1)C#N)n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1

InChI Key InChIKey=WBDTWCPQCHHYKA-BGMSHATGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 147504   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM147504(US8962608, 9)
Affinity DataIC50:  247nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM147504(US8962608, 9)
Affinity DataIC50:  12nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent