BDBM148181 US8962616, 9
SMILES Cc1nccc(n1)[C@H]1CC2CSC(N)=N[C@]2(CO1)c1ccc(F)cc1F
InChI Key InChIKey=NCFZOHVZLVQZGK-APTIMPFDSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 148181
Affinity DataIC50: >1.00E+5nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
Affinity DataIC50: 583nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair