BDBM150546 US10238633, Example 220::US8987249, 220::US9713606, 220

SMILES O=C(N[C@@H](Cc1ccc2ccccc2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2

InChI Key InChIKey=FNUIDHMDMWFOTD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 150546   

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150546(US8987249, 220 | US9713606, 220 | US10238633, Exam...)
Affinity DataIC50: 253nMpH: 6.0 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150546(US8987249, 220 | US9713606, 220 | US10238633, Exam...)
Affinity DataIC50: 253nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150546(US8987249, 220 | US9713606, 220 | US10238633, Exam...)
Affinity DataIC50: 253nMAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent