BDBM150823 US8981106, 13a::USRE47267, Compound 13a

SMILES CC(=O)Oc1ccccc1CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1

InChI Key InChIKey=STSDXVAFJXUREA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150823   

TargetC-X-C chemokine receptor type 2(Human)
Syntrix Biosystems

US Patent
LigandPNGBDBM150823(US8981106, 13a | USRE47267, Compound 13a)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetC-X-C chemokine receptor type 2(Human)
Syntrix Biosystems

US Patent
LigandPNGBDBM150823(US8981106, 13a | USRE47267, Compound 13a)
Affinity DataIC50: 5.00E+3nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent