BDBM151090 US8987273, 1-1

SMILES Cc1cn2nc(-c3ccc(cc3)C3(N)CCC3)c(cc2n1)-c1ccccc1

InChI Key InChIKey=GLOKHTIHUXDYDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151090   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM151090(US8987273, 1-1)
Affinity DataIC50: 1.73E+4nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM151090(US8987273, 1-1)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent