BDBM15216 Isoquinoline-5-sulfonic acid (2S,4R)-(4-(4-chlorobenzyloxy)pyrrolidin-2-yl-methyl)amide::N-{[(2S,4R)-4-[(4-chlorophenyl)methoxy]pyrrolidin-2-yl]methyl}isoquinoline-5-sulfonamide::isoquinoline-5-sulfonamide 48

SMILES Clc1ccc(CO[C@H]2CN[C@H](CNS(=O)(=O)c3cccc4cnccc34)C2)cc1

InChI Key InChIKey=RLNNFNGBXLTQOB-RBUKOAKNSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15216   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Uk Centre For Cancer Therapeutics

LigandPNGBDBM15216(Isoquinoline-5-sulfonic acid (2S,4R)-(4-(4-chlorob...)
Affinity DataIC50:  400nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Uk Centre For Cancer Therapeutics

LigandPNGBDBM15216(Isoquinoline-5-sulfonic acid (2S,4R)-(4-(4-chlorob...)
Affinity DataIC50:  1.70E+3nMAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed