BDBM152459 1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(3-chlorophenyl)urea (e23)

SMILES COc1cccc2cc(-c3csc(NC(=O)Nc4cccc(Cl)c4)n3)c(=O)oc12

InChI Key InChIKey=OTEOWPCRQHCXMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152459   

TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Bezmialem Vakif University

LigandPNGBDBM152459(1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl...)
Affinity DataIC50:  6.29E+4nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Bezmialem Vakif University

LigandPNGBDBM152459(1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl...)
Affinity DataIC50:  1.05E+5nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed