BDBM153932 US8999981, E2

SMILES C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(NC(=O)c3cnc(C)cn3)n[nH]c2C1(C)C

InChI Key InChIKey=NOQFNXVALFHYDE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153932   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153932(US8999981, E2)
Affinity DataKi:  72.9nM ΔG°:  -9.89kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent