BDBM155987 US9018214, 38

SMILES C[C@@H]1CN(CC(=O)N2CCc3cnc(cc23)-c2cc(Cl)ccc2F)CCN1

InChI Key InChIKey=NSAXRGNCLQSIAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 155987   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 155987BDBM155987(US9018214, 38)
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 155987BDBM155987(US9018214, 38)
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent