BDBM156065 US9018214, 116

SMILES CC1(C)CN(C(=O)CN2CCN[C@@H](CF)C2)c2cc(Cc3ccccc3)ncc12

InChI Key InChIKey=IHRHKNGNWWICAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156065   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 156065BDBM156065(US9018214, 116)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 156065BDBM156065(US9018214, 116)
Affinity DataIC50: 2.70E+4nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent