BDBM156185 US9018214, 236

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc23)[C@@H](CN2CCOCC2)CN1

InChI Key InChIKey=JRIYDCBJPOXBDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156185   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 156185BDBM156185(US9018214, 236)
Affinity DataIC50: 58nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent