BDBM157457 US9023865, 298

SMILES COC[C@@H](NC(=O)Nc1cc2[nH]nc(-c3ccnc(c3)N3CCOCC3)c2cn1)c1ccc(F)cc1

InChI Key InChIKey=AUPYVHHMCZICGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157457   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM157457(US9023865, 298)
Affinity DataIC50: 1.17nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
Go to US Patent