BDBM158110 US9024044, 38::US9227949, 38::US9655879, 38

SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccccc1

InChI Key InChIKey=LFNPOEKMAAWLGP-HXUWFJFHSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 158110   

TargetEnteropeptidase(Homo sapiens (Human))
Ajinomoto

US Patent
LigandPNGBDBM158110(US9024044, 38 | US9227949, 38 | US9655879, 38)
Affinity DataKi:  0.970nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Ajinomoto

US Patent
LigandPNGBDBM158110(US9024044, 38 | US9227949, 38 | US9655879, 38)
Affinity DataKi:  0.970nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Ajinomoto

US Patent
LigandPNGBDBM158110(US9024044, 38 | US9227949, 38 | US9655879, 38)
Affinity DataKi:  0.970nMAssay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Ajinomoto

US Patent
LigandPNGBDBM158110(US9024044, 38 | US9227949, 38 | US9655879, 38)
Affinity DataKi:  1.45nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Ajinomoto

US Patent
LigandPNGBDBM158110(US9024044, 38 | US9227949, 38 | US9655879, 38)
Affinity DataKi:  1.45nMAssay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Ajinomoto

US Patent
LigandPNGBDBM158110(US9024044, 38 | US9227949, 38 | US9655879, 38)
Affinity DataKi:  1.45nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent