BDBM158338 US9029370, 132

SMILES Fc1cc(NC(=O)c2cnn(c2)-c2ccnc(n2)C(F)(F)F)ccc1[C@H]1CNCCO1

InChI Key InChIKey=TXZHQSVRDDWWRW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158338   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM158338(US9029370, 132)
Affinity DataKi:  3.60nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat inac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM158338(US9029370, 132)
Affinity DataKi:  8nM ΔG°:  -11.5kcal/molepH: 7.4 T: 2°CAssay Description:Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
US Patent