BDBM161465 US10124003, Ref. Ex. Compound 6::US10835536, Ref. Ex. Comp 6::US10894048, Ref. Ex Comp. 6::US9108973, Ref 6

SMILES CN(C)C\C=C\C(=O)N1CC[C@@H](C1)n1nc(C#Cc2cccc(NC(C)=O)c2)c2c(N)ncnc12

InChI Key InChIKey=GSSMTELALXTHAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161465   

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161465(US9108973, Ref 6 | US10124003, Ref. Ex. Compound 6...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161465(US9108973, Ref 6 | US10124003, Ref. Ex. Compound 6...)
Affinity DataIC50: 110nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161465(US9108973, Ref 6 | US10124003, Ref. Ex. Compound 6...)
Affinity DataIC50: 110nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161465(US9108973, Ref 6 | US10124003, Ref. Ex. Compound 6...)
Affinity DataIC50: 110nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent