BDBM161544 US9108983, Example 93

SMILES COCCn1c(C)c(cc1-c1cc2OCOc2cc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1)C(=O)N(c1cnn(C)c1)c1ccc(O)cc1

InChI Key InChIKey=HGYUIDODGZWRPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161544   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161544(US9108983, Example 93)
Affinity DataIC50: 19.7nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent