BDBM16176 3-(1-adamantyl)-1-[(4-carbamimidamidophenyl)methyl]urea::3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methyl]urea::AGB::WX293T

SMILES [#7]\[#6](-[#7])=[#7]\c1ccc(-[#6]-[#7]-[#6](=O)-[#7]C23[#6]-[#6]-4-[#6]-[#6](-[#6]-[#6](-[#6]-4)-[#6]2)-[#6]3)cc1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16176   

TargetUrokinase-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16176(3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methy...)
Affinity DataKi:  2.40E+3nM ΔG°:  -7.66kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16176(3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methy...)
Affinity DataKi:  4.60E+4nM ΔG°:  -5.91kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16176(3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methy...)
Affinity DataKi: >1.00E+6nM ΔG°: >-4.09kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed