BDBM163370 US9687479, 264 tert-butyl2-[3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1H-pyrazol-3-yl)-2-oxo-1,2-dihydropyridin-1-yl]acetate

SMILES CC(C)(C)OC(=O)Cn3cccc(c2cc(NCc1ccc(Cl)s1)n[nH]2)c3=O

InChI Key InChIKey=LRACRGKZXIFIMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163370   

TargetProthrombin(Human)
Verseon

US Patent
LigandPNGBDBM163370(US9687479, 264 tert-butyl2-[3-(5-[(5-chlorothiophe...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent