BDBM164214 US9669028, 164 2-(4-(3-((3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)amino)benzyl)piperazin-1-yl)ethanol

SMILES Cc1n[nH]c2ncc(Nc3cccc(CN4CCN(CCO)CC4)c3)cc12

InChI Key InChIKey=DSKNPNGFFNCMHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164214   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM164214(US9669028, 164 2-(4-(3-((3-methyl-1H-pyrazolo[3,4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM164214(US9669028, 164 2-(4-(3-((3-methyl-1H-pyrazolo[3,4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent