BDBM164412 US9066954, 38

SMILES COc1ccc2c(OCc3nnc4ccc(cn34)-c3cccc(=O)[nH]3)ccnc2c1

InChI Key InChIKey=KQHFGWJQEIPNKJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164412   

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandPNGBDBM164412(US9066954, 38)
Affinity DataKi:  37nM ΔG°:  -10.2kcal/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent