BDBM164551 US9067871, 38

SMILES CC(C)(C)OC(=O)NC1CCc2ccc(CN)cc2C1Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=NIWMRCBQHHQCIN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164551   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164551(US9067871, 38)
Affinity DataIC50: 1.00E+5nMAssay Description:[3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c5_CHO cells were plated at 20,000 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164551(US9067871, 38)
Affinity DataKi: <1.00E+5nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent